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from$138
See prices from 18 sites
21c Museum Hotel Louisville
21c Museum Hotel Louisville
21c Museum Hotel Louisville
21c Museum Hotel Louisville
21c Museum Hotel Louisville

Good to know

  • Acclaimed Proof on Main dining

    Savor award-winning cuisine and an extensive bourbon collection at the on-site restaurant, known for its vibrant decor and locally sourced menu.

  • Artistic bathroom nightlight features

    Enjoy thoughtful room details like black-light bathroom settings that create a glowing blue ambiance and designer toiletries for a spa-like feel.

  • Full-service wellness sanctuary

    Relax and recharge with on-site spa treatments, a sauna, and a steam room, or maintain your routine in the well-appointed 24-hour fitness center.

  • Historic Museum Row location

    Explore downtown Louisville from West Main Street, situated steps from the Louisville Slugger Museum and just a 10-minute walk to Whiskey Row.

  • Rooftop apartment with garden

    Elevate your visit in the exclusive rooftop suite, which offers a full kitchen and a private garden terrace overlooking the Louisville streetscape.

  • Iconic migrating Red Penguins

    Discover the hotel's signature life-sized sculptures that move throughout the property daily, adding a whimsical and interactive touch to your stay.

This summary was created by AI and might not be 100% accurate.

About 21c Museum Hotel Louisville

This boutique four star hotel is set on Museum Row, and is within walking distance of the Louisville Slugger Museum, and boasts on-site banquet facilities. The modern rooms at 21c Museum Hotel Louisville - MGallery feature Nespresso machines and complimentary Wi-Fi, while en suite bathrooms include luxurious vanities. Upscale suites add a separate seating area. Amenities at this hotel include a fully fitted gym for the young at heart, while the business center, valet parking and an art museum are added amenities. The on-site restaurant, Proof on Main, serves both local and international cuisine, while room service is available 24/7. The bar at Proof serves seasonal specialty cocktails and a variety of other drinks. The Louisville Glassworks is within a five minute walk of 21c Museum Hotel Louisville - MGallery, or enjoy an outing to the Kentucky Center for the Performing Arts, just a three minute walk away.

Rooms

  • Deluxe Double Room, 2 Double Beds

    • 1 2 Double Beds
    • Sleeps 4
    • 335 sq ft

  • Luxury Double Room, 2 Double Beds

    • 1 2 Double Beds
    • Sleeps 4
    • 435 sq ft

  • Suite, Corner

    • 1 1 King Bed
    • Sleeps 3

  • Deluxe Room, 1 King Bed

    • 1 1 King Bed
    • Sleeps 3
    • 350 sq ft

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  • Spa
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Price trend

Based on lowest prices on trivago from the last 30 days
$660
$330
$0

Tue, 09/15/26

$294

Wed, 09/16/26

$560

Thu, 09/17/26

$326

Fri, 09/18/26

$424

Sat, 09/19/26

$475

Sun, 09/20/26

$243

Mon, 09/21/26

$264

Tue, 09/22/26

$284

Wed, 09/23/26

$353

Thu, 09/24/26

N/A

Fri, 09/25/26

$453

Sat, 09/26/26

N/A

Sun, 09/27/26

$534

Mon, 09/28/26

$225

Tue, 09/29/26

$284

Wed, 09/30/26

$264

Thu, 10/01/26

$268

Fri, 10/02/26

$377

Sat, 10/03/26

$435

Sun, 10/04/26

$174

Mon, 10/05/26

$199

Tue, 10/06/26

$293

Wed, 10/07/26

$352

Thu, 10/08/26

$267

Fri, 10/09/26

$395

Sat, 10/10/26

$292

Sun, 10/11/26

$199

Mon, 10/12/26

$660

Tue, 10/13/26

$486

Wed, 10/14/26

$545

Thu, 10/15/26

$242

Fri, 10/16/26

$377

Sat, 10/17/26

$387

Sun, 10/18/26

$267

Mon, 10/19/26

$267

Tue, 10/20/26

$452

Wed, 10/21/26

$454

Thu, 10/22/26

$297

Fri, 10/23/26

$435

Sat, 10/24/26

$361

Sun, 10/25/26

$182

Mon, 10/26/26

$171

Tue, 10/27/26

$216

Wed, 10/28/26

$199

Thu, 10/29/26

$208

Fri, 10/30/26

$183

Sat, 10/31/26

$214

Sun, 11/01/26

$250

Mon, 11/02/26

$265

Tue, 11/03/26

$327

Wed, 11/04/26

$373

Thu, 11/05/26

$344

Fri, 11/06/26

$208

Sat, 11/07/26

$225

Sun, 11/08/26

$157

Mon, 11/09/26

$157

Tue, 11/10/26

$199

Wed, 11/11/26

$215

Thu, 11/12/26

$199

Fri, 11/13/26

$224

Sat, 11/14/26

$195

Sun, 11/15/26

$169

Reviews

9.2
Excellent
based on 5,780 ratings from top 
sites

Review summary

Summarized by AI from 900+ reviews

This hotel is a vibrant urban hub catering to luxury travelers, sightseers, and groups of friends seeking a unique and immersive experience. Its excellent location in downtown Louisville provides easy walking access to major attractions like the Louisville Slugger Museum, Muhammad Ali Center, and numerous Bourbon distilleries along Whiskey Row. The property distinguishes itself with a unique blend of facilities, notably functioning as an art museum with thought-provoking installations and rotating exhibits. Guests consistently praise the welcoming and professional staff and service, and the on-site restaurant, Proof on Main, is frequently highlighted for its exceptional food and cocktails. For a truly distinctive stay, consider booking the "Asleep in the Cyclone" room, an immersive art installation that doubles as a guest room.

Rated above average for Louisville

Guest reviews

Excellent74%
Very good13%
Good6%
Fair4%
Poor3%

Top amenities

  • WiFi in lobby
  • WiFi in rooms
  • Spa
  • Pets
  • A/C
  • Restaurant
  • Hotel bar
  • Gym

All amenities

Wellness

  1. Beauty salon
  2. Steam room
  3. Massage
  4. Sauna
  5. Body treatments
  6. Hammam
  7. Bathrobe

Property amenities

  1. Business center
  2. Gym
  3. Bell service
  4. Pet-friendly
  5. Bar
  6. Conference rooms
  7. Non-smoking rooms
  8. Restaurant
  9. 24-hour reception
  10. Laundry service
  11. Spa
  12. WiFi in public areas

For children

  1. Crib

Accessibility

  1. Wheelchair accessible
  2. Accessible parking

Room amenities

  1. Shower
  2. Ironing board
  3. Openable windows
  4. Television
  5. Hairdryer
  6. Central heating
  7. Air conditioning
  8. Minibar
  9. Satellite TV
  10. Desk
  11. Small lounge
  12. Telephone

Sports facilities

  1. Fitness
  2. Yoga

Hotel theme/type

  1. Convention hotel
  2. Boutique hotel

Location

700 W Main St, Louisville, 40202, USA

Distance from 21c Museum Hotel Louisville

Muhammad Ali Center:0.1 miles

Louisville Slugger Museum & Factory:0.1 miles

:0.2 miles

KFC Yum! Center:0.4 miles

Belle of Louisville:0.4 miles

Transit Authority of River City:0.8 miles

Louisville Slugger Field:0.9 miles

Lynn Family Stadium:1.6 miles

J B Speed Art Museum:2.7 miles

L&N Federal Credit Union Stadium:3.5 miles

Louisville Zoo:4.7 miles

Louisville Muhammad Ali International Airport:5.9 miles

Explore nearby attractions

Property info

700 W Main St, Louisville, 40202, USA

Frequently Asked Questions about 21c Museum Hotel Louisville

  • Is there a pool area at 21c Museum Hotel Louisville?

    No, 21c Museum Hotel Louisville doesn’t offer pool areas.

  • Are pets allowed at 21c Museum Hotel Louisville?

    Yes, 21c Museum Hotel Louisville has a pet policy that may vary based on the room type or availability. Please check with the hotel directly to learn about their pet policy.

  • Is parking available at 21c Museum Hotel Louisville?

    Yes, 21c Museum Hotel Louisville provides Accessible parking for guests.

  • What time is check-in and check-out at 21c Museum Hotel Louisville?

    Check-in at 21c Museum Hotel Louisville is available from: . Check-out time is by .

  • Where is 21c Museum Hotel Louisville located?

    21c Museum Hotel Louisville is located at 700 W Main St, 40202, Louisville, USA.

The prices and availability we receive from booking sites change constantly. This means you may not always find the exact same offer you saw on trivago when you land on the booking site.

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